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Article

In Vivo Regulation of Hepatitis B Virus Replication by Peroxisome Proliferators

1 Dec 1999

Abstract excerpt

The role of the peroxisome proliferator-activated receptor alpha (PPARalpha) in regulating hepatitis B virus (HBV) transcription and replication in vivo was investigated in an HBV transgenic mouse model. Treatment of HBV transgenic mice with the peroxisome proliferators Wy-14,643 and clofibric acid resulted in a less than twofold increase in HBV transcription rates and steady-state levels of HBV RNAs in the...

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PMID: 10559356
DOI: 10.1128/jvi.73.12.10377-10386.1999

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In Vivo Regulation of Hepatitis B Virus Replication by Peroxisome ProliferatorsPMID 10559356Read ↗

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