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Article

Essential role for Schizosaccharomyces pombe pik1 in septation.

PloS one - 9 Jul 2009

Park Jae-Sook, Steinbach Sarah K, Desautels Michel, Hemmingsen Sean M

Abstract excerpt

BACKGROUND: Schizosaccharomyces pombe pik1 encodes a phosphatidylinositol 4-kinase, reported to bind Cdc4, but not Cdc4(G107S). PRINCIPAL FINDINGS: Gene deletion revealed that pik1 is essential. In cells with pik1 deleted, ectopic expression of a loss-of-function allele, created by fusion to a temperature-sensitive dihydrofolate reductase, allowed normal cell proliferation at 25 degrees C. At 36 degrees C, cells...

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Identifiers

PMID: 19587793
DOI: 10.1371/journal.pone.0006179
PMCID: PMC2704394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Essential role for Schizosaccharomyces pombe pik1 in septation.PMID 19587793Read ↗

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