Article
Overexpression of myogenin in muscles of transgenic mice: interaction with Id-1, negative crossregulation of myogenic factors, and induction of extrasynaptic acetylcholine receptor expression.
Molecular and cellular biology - 1 Dec 1995
Gundersen K, Rabben I, Klocke B J, Merlie J P
Abstract excerpt
To investigate the role of myogenin in regulating acetylcholine receptor expression in adult muscle, this muscle-specific basic helix-loop-helix transcription factor was overexpressed in transgenic mice by using regulatory elements conferring strong expression confined to differentiated postmitot...
Topics
- Aging
- Animals
- Animals, Newborn
- Cell Membrane
- DNA-Binding Proteins
- Embryo, Mammalian
- Gene Expression
- Gene Expression Regulation
- Genotype
- Helix-Loop-Helix Motifs
- Inhibitor of Differentiation Protein 1
- Macromolecular Substances
- Mice
- Mice, Transgenic