Article
Breeding of the gad-mdx mouse: influence of genetically induced denervation on dystrophic muscle fibers.
Laboratory animal science - 1 Feb 1994
Suh J G, Yamazaki A, Tomita T
Abstract excerpt
A new double mutant mouse strain, gad-mdx, was established. The transmission of mdx and gad genes was monitored by determining their chemical markers, creative kinase activity and phosphoglucomutase-1 isoenzyme, respectively, in blood samples. This new strain was characterized by high creatine ki...
Topics
- Animals
- Breeding
- Creatine Kinase
- Dystrophin
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Muscle Denervation
- Muscles
- Muscular Dystrophy, Animal
- Mutation
- Necrosis
