Article
Breeding of the gad-mdx mouse: influence of genetically induced denervation on dystrophic muscle fibers.
Laboratory animal science - 1 Feb 1994
Suh J G, Yamazaki A, Tomita T
Abstract excerpt
A new double mutant mouse strain, gad-mdx, was established. The transmission of mdx and gad genes was monitored by determining their chemical markers, creative kinase activity and phosphoglucomutase-1 isoenzyme, respectively, in blood samples. This new strain was characterized by high creatine kinase activity in the plasma, lack of dystrophin in the muscle, and the presence of axonal swellings in the neural...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
