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Tombola, a tesmin/TSO1-family protein, regulates transcriptional activation in the Drosophila male germline and physically interacts with always early.

Development (Cambridge, England) - 1 Apr 2007

Jiang Jianqiao, Benson Elizabeth, Bausek Nina, Doggett Karen, White-Cooper Helen

Abstract excerpt

During male gametogenesis, a developmentally regulated and cell type-specific transcriptional programme is activated in primary spermatocytes to prepare for differentiation of sperm. The Drosophila aly-class meiotic-arrest loci (aly, comr, achi/vis and topi) are essential for activation of transcription of many differentiation-specific genes, and several genes important for meiotic cell cycle progression, thus...

Topics

Amino Acid Sequence
Animals
Cell Cycle Proteins
Cell Differentiation
Cell Nucleus
Drosophila
Drosophila Proteins
Male
Molecular Sequence Data
Mutation
Nuclear Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Binding

Spermatocytes

Transcriptional Activation

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Identifiers

PMID: 17360778
DOI: 10.1242/dev.000521
PMCID: PMC2229809

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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