Article
In-vitro development of resistance to beta-lactam antibiotics in Streptococcus pneumoniae.
The Journal of antimicrobial chemotherapy - 1 Aug 1995
Carsenti-Etesse H, Durant J, De Salvador F, Bensoussan M, Bensoussan F, Pradier C, Thabaut A, Dellamonica P
Abstract excerpt
Selection of resistant mutants was induced in broth by exposing pneumococci to serial sub-inhibitory concentrations of various beta-lactam antibiotics. Aminopenicillins selected for resistance to themselves and to cephalosporins although cephalosporins tended to select for resistance to their own...
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