Article
A comparative in-vitro evaluation of resistance selection after exposure to teicoplanin, vancomycin, linezolid and quinupristin-dalfopristin in Staphylococcus aureus and Enterococcus spp.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Jun 2008
Drago L, Nicola L, De Vecchi E
Abstract excerpt
The ability of breakpoint and serum concentrations of teicoplanin, vancomycin, linezolid and quinupristin-dalfopristin to select resistance was compared for isolates of methicillin-susceptible Staphylococcus aureus (MSSA), methicillin-resistant S. aureus (MRSA), Enterococcus faecalis and Enterococcus faecium. Mutation frequencies were always <10(-10), except for two isolates grown in the presence of teicoplanin...
Topics
- Acetamides
- Anti-Bacterial Agents
- Colony Count, Microbial
- Drug Resistance, Bacterial
- Enterococcus faecalis
- Enterococcus faecium
- Linezolid
- Methicillin Resistance
- Microbial Sensitivity Tests
- Mutation
- Oxazolidinones
- Selection, Genetic