Article
In vivo characterization of immunogenicity of a mitoxantrone-resistant murine P388 leukemia.
In vivo (Athens, Greece) - 1 Jan 2000
Fichtner I, Reipert B, Becker M, Lemm M
Abstract excerpt
The Mitoxantrone-resistant murine leukemia P388/Mitox, expressing the multidrug-resistant phenotype, has a higher immunogenicity than the parent sensitive P388. This could be shown in vivo by immunization with lethally-irradiated tumor cells. If the P388/Mitox was used for immunization before subsequent challenge with viable tumor cells of the same line, this resulted in a partial rejection of tumors and...
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