Article
Role of p38 MAPK in the cytokine reprogramming of a human leukemic cell line with a drug-resistant phenotype.
Cell communication and signaling : CCS - 29 Jan 2026
Cadenas-Garrido Paula, García-Serna Azahara M, Parrado Antonio, Martínez-García Javier, Herrera-Suarez Marcela, Cánovas Manuel, de Diego Puente Teresa, Saceda Miguel, Pelegrin Pablo, Díaz-Carrasco María Sacramento, Martín-Orozco Elena
Abstract excerpt
BACKGROUND: Tumor cells have the capacity to develop coordinated resistance mechanisms that promote their survival and progression through the acquisition of multidrug resistance (MDR). This phenotype is the consequence of global cellular changes caused by antineoplastic drugs and may include modifications in the secretome, which influence the antitumoral immune response and the fate of resistant cells. RESULTS:...
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