Article
Rapid detection of Chinese G gamma+(A gamma delta beta)zero-thalassemia by polymerase chain reaction.
Acta haematologica - 1 Jan 1993
Ko T M, Tseng L H, Hsieh F J, Chuang S M, Lee T Y
Abstract excerpt
The Chinese G gamma+(A gamma delta beta)zero-thalassemia is caused by a deletion of more than 80 kilobases. It has a beta(+)-thalassemia phenotype and should be differentiated from other mutations causing beta-thalassemia. Using polymerase chain reaction with three oligonucleotide primers bridgin...
Topics
- Alleles
- Base Sequence
- Chromosome Deletion
- Genetic Carrier Screening
- Globins
- Humans
- Molecular Sequence Data
- Oligonucleotide Probes
- Polymerase Chain Reaction
- Taiwan
- beta-Thalassemia