Article
Gallstone cholesterol content is related to apolipoprotein E polymorphism.
Gastroenterology - 1 Jun 1993
Juvonen T, Kervinen K, Kairaluoma M I, Lajunen L H, Kesäniemi Y A
Abstract excerpt
BACKGROUND: The genetically determined phenotypes of apolipoprotein E are related to variations in lipoprotein levels and in the enterohepatic metabolism of cholesterol and bile acids. The present study was designed to elucidate the role of apolipoprotein E polymorphism in gallstone formation. ME...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Apolipoproteins E
- Bile
- Cholelithiasis
- Cholesterol
- Crystallization
- Female
- Humans
- Male
- Middle Aged
- Phenotype
- Polymorphism, Genetic
