Article
Gallstones: genetics versus environment.
Annals of surgery - 1 Jun 2002
Nakeeb Attila, Comuzzie Anthony G, Martin Lisa, Sonnenberg Gabriele E, Swartz-Basile Debra, Kissebah Ahmed H, Pitt Henry A
Abstract excerpt
OBJECTIVE: The aim of this study was to determine if a significant genetic component contributes to the pathogenesis of symptomatic gallstones. SUMMARY BACKGROUND DATA: Gallstones represent a polygenic disorder that affects more than 30,000,000 Americans and results in more than 750,000 cholecystectomies in the United States annually. Risk factors include age, gender, race, parity, obesity, and diabetes. A family...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Cholelithiasis
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Risk Factors