Article
Apolipoprotein-E genotype and the risk of developing cholelithiasis following bariatric surgery: a clue to prevention of routine prophylactic cholecystectomy.
Obesity surgery - 1 Jun 2002
Abu Abeid Subhi, Szold Amir, Gavert Nancy, Goldiner Ilana, Grynberg Elisheva, Peretz Hava, Konikoff Fred M
Abstract excerpt
BACKGROUND: Obesity and especially rapid weight loss following bariatric surgery are known risk factors for cholelithiasis. Since the risk may be high, prophylactic cholecystectomy has been advocated. Apolipoprotein (Apo) E, an important carrier protein in cholesterol metabolism and trafficking, is believed to play a role in gallstone pathogenesis. In particular, the Apo E4 allele has been suggested to be...
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