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Article

Expression of an extracellular deletion of Xotch diverts cell fate in Xenopus embryos.

Cell - 21 May 1993

Coffman C R, Skoglund P, Harris W A, Kintner C R

Abstract excerpt

Xotch is a Xenopus homolog of Notch, a receptor involved in cell fate decisions in Drosophila. Using an extracellular deletion construct, Xotch delta E, we show that Xotch has a similar role in Xenopus embryos. Broad expression causes the loss of dorsal structures and the expansion and disorganiz...

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PMID: 8500162
DOI: 10.1016/0092-8674(93)90247-n

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8500162-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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