Article
Role of the gamma component of preprotoxin in expression of the yeast K1 killer phenotype.
Yeast (Chichester, England) - 1 Mar 1993
Zhu Y S, Kane J, Zhang X Y, Zhang M, Tipper D J
Abstract excerpt
K1 killer strains of Saccharomyces cerevisiae secrete a polypeptide toxin to which they are themselves immune. The alpha and beta components of toxin comprise residues 45-147 and 234-316 of the 316-residue K1 preprotoxin. The intervening 86-residue segment is called gamma. A 26-residue signal peptide is removed on entry into the endoplasmic reticulum. The Kex2 protease excises the toxin components from the...
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