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Article

The variability of the hepatitis B virus genome: statistical analysis and biological implications.

Molecular biology and evolution - 1 Mar 1993

Lauder I J, Lin H J, Lau J Y, Siu T S, Lai C L

Abstract excerpt

A statistical analysis of the nucleotide sequence variability in 14 published hepatitis B virus (HBV) genomes was carried out using parametric and nonparametric methods. A parametric statistical model revealed that the different regions of the genome differed significantly in their variability. The conclusion was supported by a nonparametric kernel-density model of the HBV genome. Genes S, C, and P, region X, the...

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Identifiers

PMID: 8487640
DOI: 10.1093/oxfordjournals.molbev.a040013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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