Molecular evolution of the hepatitis B virus genome.

doi:10.1007/BF00175817

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Article

Molecular evolution of the hepatitis B virus genome.

Journal of molecular evolution - 1 Nov 1995

Yang Z, Lauder I J, Lin H J

Abstract excerpt

The hepatitis B virus (HBV) has a circular DNA genome of about 3,200 base pairs. Economical use of the genome with overlapping reading frames may have led to severe constraints on nucleotide substitutions along the genome and to highly variable rates of substitution among nucleotide sites. Nucleo...

Topics

Codon
Evolution, Molecular
Genes, Viral
Genetic Variation
Genome, Viral
Hepatitis B virus
Likelihood Functions
Models, Genetic
Mutagenesis
Phylogeny
Species Specificity
Time Factors

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