Article
Phenotypic analysis of a resting subpopulation of human peripheral blood NK cells: the FcR gamma III (CD16) molecule and NK cell differentiation.
Immunology - 1 Jan 1991
Warren H S, Skipsey L J
Abstract excerpt
A subpopulation of human peripheral blood natural killer (NK) cells, defined by sedimentation at Percoll high buoyant densities (P greater than 1.0635-1.0640 g/ml) and unresponsiveness to interleukin-2 (IL-2), contained two distinct populations based on the intensity of CD16 (FcR gamma III) expression, namely CD16dim and CD16bright. This resting subpopulation of NK cells differed from the total population of...
Topics
- Antigens, CD
- Antigens, Differentiation
- Cell Differentiation
- Cytotoxicity Tests, Immunologic
- Flow Cytometry
- Humans
- Interleukin-2
- Killer Cells, Natural
- Phenotype
- Receptors, Fc
- Receptors, IgG
