Article
Loss of heterozygosity for loci on chromosome 10 is associated with morphologically malignant meningioma progression.
Cancer research - 15 May 1993
Rempel S A, Schwechheimer K, Davis R L, Cavenee W K, Rosenblum M L
Abstract excerpt
Meningioma is a common tumor of the central nervous system which displays morphological heterogeneity. In order to determine whether this phenotypic variability is associated with distinct or overlapping genetic lesions, we compared genotypes at several loci defined by allele length polymorphism in tumor and normal tissues from patients with meningioma. In particular, we concentrated on loci on chromosomes 22 and...
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