Article
Potentiation and antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin effects in a complex environmental mixture.
Toxicology and applied pharmacology - 1 Apr 1993
Silkworth J B, Cutler D S, O'Keefe P W, Lipinskas T
Abstract excerpt
There is increasing need to understand the toxicity of complex environmental mixtures. The organic phase of a leachate (OPL) from the Love Canal chemical dump site is a complex mixture that contains over 100 organic compounds, including 0.74 ppm 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Mice co...
Topics
- Animals
- Aryl Hydrocarbon Hydroxylases
- Dose-Response Relationship, Drug
- Environmental Pollutants
- Enzyme Induction
- Hazardous Waste
- Immune Tolerance
- Liver
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred Strains
- New York
- Organ Size
- Phenotype
- Polychlorinated Dibenzodioxins
- Receptors, Drug
- Species Specificity