Article
Toxicological potency of 2,3,7,8-tetrachlorodibenzo-p-dioxin relative to 100 other compounds: a relative potency analysis of in vitro and in vivo test data.
Archives of environmental contamination and toxicology - 1 Jul 1995
Jones T D
Abstract excerpt
A common definition of relative potency is the dose of a reference compound required to cause a particular incidence of a specific toxic response divided by the dose of a test compound needed to cause an equal incidence of that same effect. In this simple manner, toxicological assessments for a c...
Topics
- Animals
- Biological Assay
- Carcinogens
- DNA
- DNA Damage
- Female
- Humans
- In Vitro Techniques
- Mice
- Mutation
- Polychlorinated Dibenzodioxins
- Pregnancy
- Rats
- Reference Standards
- Structure-Activity Relationship