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Article

Triggering of murine NK cells by CD40 and CD86 (B7-2).

Journal of immunology (Baltimore, Md. : 1950) - 15 May 1999

Martín-Fontecha A, Assarsson E, Carbone E, Kärre K, Ljunggren H G

Abstract excerpt

NK cell-mediated cytotoxicity is regulated by both triggering and inhibitory signals. The interaction between MHC class I molecules expressed on target cells and specific MHC class I-binding receptors expressed by NK cells generally leads to inhibition of lysis. We have shown recently that CD80 (B7-1) in mice and CD40 in humans trigger NK cell-mediated cytotoxicity in vitro. In the present study, we show that...

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Identifiers

PMID: 10229827

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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