Article
Effects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoprotein.
Journal of virology - 1 May 1993
Cao J, Bergeron L, Helseth E, Thali M, Repke H, Sodroski J
Abstract excerpt
Changes were introduced into conserved amino acids within the ectodomain of the human immunodeficiency virus type 1 (HIV-1) gp41 transmembrane envelope glycoprotein. The effect of these changes on the structure and function of the HIV-1 envelope glycoproteins was examined. The gp41 glycoprotein c...
Topics
- Acquired Immunodeficiency Syndrome
- Amino Acids
- CD4 Antigens
- HIV Envelope Protein gp120
- HIV Envelope Protein gp41
- HIV-1
- Membrane Fusion
- Mutagenesis, Site-Directed
- Neutralization Tests
- Phenotype
- Protein Processing, Post-Translational