Article
Amino acid changes in the fourth conserved region of human immunodeficiency virus type 2 strain HIV-2ROD envelope glycoprotein modulate fusion.
Journal of virology - 1 Oct 1993
Keller R, Peden K, Paulous S, Montagnier L, Cordonnier A
Abstract excerpt
The fourth conserved region (C4) of human immunodeficiency virus type 1 (HIV-1) surface glycoprotein has been shown to participate in CD4 binding and to influence viral tropism (A. Cordonnier, L. Montagnier, and M. Emerman, Nature [London] 340:571-574, 1989). To define the role of the correspondi...
Topics
- Amino Acid Sequence
- Base Sequence
- CD4 Antigens
- Cell Line
- Codon
- Conserved Sequence
- Cysteine
- DNA, Viral
- Giant Cells
- HIV Long Terminal Repeat
- HIV-2
- HeLa Cells
- Humans
- Membrane Fusion
- Methionine
- Mutagenesis, Site-Directed
- Phenotype
- Plasmids