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Article

Amino acid changes in the fourth conserved region of human immunodeficiency virus type 2 strain HIV-2ROD envelope glycoprotein modulate fusion.

Journal of virology - 1 Oct 1993

Keller R, Peden K, Paulous S, Montagnier L, Cordonnier A

Abstract excerpt

The fourth conserved region (C4) of human immunodeficiency virus type 1 (HIV-1) surface glycoprotein has been shown to participate in CD4 binding and to influence viral tropism (A. Cordonnier, L. Montagnier, and M. Emerman, Nature [London] 340:571-574, 1989). To define the role of the corresponding region of HIV-2, we introduce single amino acid changes into the C4 sequence of HIV-2ROD. The effects of these...

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Identifiers

PMID: 8371358
DOI: 10.1128/JVI.67.10.6253-6258.1993
PMCID: PMC238048

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