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Article

Mutational analysis of residues in the coiled-coil domain of human immunodeficiency virus type 1 transmembrane protein gp41.

Journal of virology - 1 Dec 1998

Weng Y, Weiss C D

Abstract excerpt

The envelope glycoprotein (Env) of human immunodeficiency virus mediates virus entry into cells by undergoing conformational changes that lead to fusion between viral and cellular membranes. A six-helix bundle in gp41, consisting of an interior trimeric coiled-coil core with three exterior helices packed in the grooves (core structure), has been proposed to be part of a fusion-active structure of Env (D. C. Chan,...

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Identifiers

PMID: 9811701
DOI: 10.1128/JVI.72.12.9676-9682.1998
PMCID: PMC110477

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Mutational analysis of residues in the coiled-coil domain of human immunodeficiency virus type 1 transmembrane protein gp41.PMID 9811701Read ↗

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