Article
Mycobacterial RNA polymerase forms unstable open promoter complexes that are stabilized by CarD.
Nucleic acids research - 1 Jan 2015
Davis Elizabeth, Chen James, Leon Katherine, Darst Seth A, Campbell Elizabeth A
Abstract excerpt
Escherichia coli has served as the archetypal organism on which the overwhelming majority of biochemical characterizations of bacterial RNA polymerase (RNAP) have been focused; the properties of E. coli RNAP have been accepted as generally representative for all bacterial RNAPs. Here, we directly compare the initiation properties of a mycobacterial transcription system with E. coli RNAP on two different...
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