Article
Slow N-acetylation as a possible contributor to bladder carcinogenesis.
Molecular carcinogenesis - 1 Sept 2020
El Kawak Michelle, Dhaini Hassan R, Jabbour Michel E, Moussa Mohamad A, El Asmar Khalil, Aoun Mona
Abstract excerpt
Bladder cancer (BCa) is an exophytic tumor that presents as either noninvasive confined to the mucosa (NMIBC) or invading the detrusor muscle (MIBC), and was recently further subgrouped into molecular subtypes. Arylamines, major BCa environmental and occupational risk factors, are mainly metabolized by the genetically polymorphic N-acetyltransferases 1, NAT1 and NAT2. In this study, we investigated the...
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