Article
Ligand diffusion in the distal heme pocket of myoglobin. A primary determinant of geminate rebinding.
The Journal of biological chemistry - 5 Apr 1993
Ikeda-Saito M, Dou Y, Yonetani T, Olson J S, Li T, Regan R, Gibson Q H
Abstract excerpt
There are at least two picosecond kinetic components in the rebinding of NO to native sperm whale myoglobin. Petrich et al. (Petrich, J. W., Lambry, J.-C., Kuczera, K., Karplus, M., Poyart, C., and Martin, J.-L. (1991) Biochemistry 30, 3975-3987) attribute the slowing of the reaction to a movement of the iron atom out of the plane of the heme following ligand dissociation. In contrast, Gibson et al. (Gibson, Q....
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