Myoglobin mutants giving the largest geminate yield in CO rebinding in the nanosecond time domain.

doi:10.1016/S0006-3495(98)77662-3

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Article

Myoglobin mutants giving the largest geminate yield in CO rebinding in the nanosecond time domain.

Biophysical journal - 1 Nov 1998

Sugimoto T, Unno M, Shiro Y, Dou Y, Ikeda-Saito M

Abstract excerpt

We have measured the rebinding of carbon monoxide (CO) to some distal mutants of myoglobin (Mb) in the time range from 10(-8) to 10(-1) s by flash photolysis, in which the photodissociated CO rebinds to the heme iron without escaping to the solvent water from the protein matrix. We have found tha...

Topics

Carbon Monoxide
Heme
Kinetics
Magnetic Resonance Spectroscopy
Models, Molecular
Mutation
Myoglobin
Photolysis
Protein Binding
Recombinant Proteins
Spectrum Analysis, Raman

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