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Article

Why are some genetic diseases common? Distinguishing selection from other processes by molecular analysis of globin gene variants.

Human genetics - 1 Mar 1993

Flint J, Harding R M, Clegg J B, Boyce A J

Abstract excerpt

Various processes (selection, mutation, migration and genetic drift) are known to determine the frequency of genetic disease in human populations, but so far it has proved almost impossible to decide to what extent each is responsible for the presence of a particular genetic disease. The techniques of gene and haplotype analysis offer new hope in addressing this issue, and we review relevant studies of three...

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PMID: 8462981
DOI: 10.1007/BF00222709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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