Article
To do tissue culture in two or three dimensions? that is the question
1 Jan 1993
Abstract excerpt
Alexis Carrel introduced the in vitro culture of tissues in the beginning of the century utilizing a culture system that allowed the three-dimensional growth of tissues. Leighton improved upon this system by developing a substrate of sponge matrices. Other methods of three-dimensional culture include collagen gels and what are known as organ culture systems on filters or meshes. In addition, cell suspensions can...
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