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Article

Three-dimensional tissue culture model of human breast cancer for the evaluation of multidrug resistance

29 Jul 2018

Abstract excerpt

Multidrug resistance (MDR) is one of the major obstacles to improving outcomes of chemotherapy in tumour patients. However, progress has been slow to overcome this phenomenon due to the limitations of current cell/tissue models in recapitulating MDR behaviour of tumour cells in vitro. To address this issue, a more pathologically relevant, three-dimensional (3D) culture of human breast cancer cells was developed...

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PMID: 30055109
DOI: 10.1002/term.2729

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