Three‑dimensional cell culture: A powerful tool in tumor research and drug discovery (Review)

Abstract excerpt

In previous years, three‑dimensional (3D) cell culture technology has become a focus of research in tumor cell biology, using a variety of methods and materials to mimic the in vivo microenvironment of cultured tumor cells ex vivo. These 3D tumor cells have demonstrated numerous different characteristics compared with traditional two‑dimensional (2D) culture. 3D cell culture provides a useful platform for further...