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Establishment and characterization of an in vitro 3D ovarian cancer model for drug screening assays

9 Jun 2020

Abstract excerpt

The acquired drug chemoresistance represents the main challenge of the ovarian cancer treatment. In addition, the absence of an adequate in vitro model able to reproduce the native tumor environment can contribute to the poor success rate of pre-clinical studies of new compounds. Three-dimensional (3D) culture models have been recently used for drug screening purposes due to their ability to reproduce the main...

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PMID: 32519461
DOI: 10.1002/btpr.3034

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