Article
Interstrain differences in murine daunomycin-induced nephrosis.
Nephron - 1 Jan 1993
Kimura M, Takahasi H, Ohtake T, Sato T, Hishida A, Nishimura M, Honda N
Abstract excerpt
Examining 8 inbred murine strains [A/J, BALB/c, SM/J, C3H/J, SWR/J, C57BL/6J (B6), DBA-2, B10D2/old (B10D2/o)] for urinary albumin excretion after a single daunomycin (DM) injection (20 mg/kg), we found strain specificity in susceptibility to DM nephrosis. This specificity did not relate to the serum disappearance rate of this drug. A/J and BALB/c were highly susceptible to the nephrosis while C57BL/6J, DBA-2 and...
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