Assembly of functional Sindbis virus RNA replication complexes: requirement for coexpression of P123 and P34

doi:10.1128/jvi.67.4.1905-1915.1993

Article

Assembly of functional Sindbis virus RNA replication complexes: requirement for coexpression of P123 and P34

1 Apr 1993

Abstract excerpt

A vaccinia virus transient expression system was used to determine which of the Sindbis virus (SIN) proteins and/or polyproteins are necessary for the formation of active replication complexes and, in particular, to analyze the role of nsP4, the putative polymerase, versus P34 in RNA replication. We generated vaccinia virus recombinants in which the cDNA for the entire SIN nonstructural coding region as well as...

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