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Article

Complexes of Sendai virus NP-P and P-L proteins are required for defective interfering particle genome replication in vitro

1 Aug 1992

Abstract excerpt

We present evidence that the formation of NP-P and P-L protein complexes is essential for replication of the genome of Sendai defective interfering (DI-H) virus in vitro, using extracts of cells expressing these viral proteins from plasmids. Optimal replication of DI-H nucleocapsid RNA required extracts of cells transfected with critical amounts and ratios of each of the plasmids and was three- to fivefold better...

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PMID: 1321276
DOI: 10.1128/jvi.66.8.4901-4908.1992

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