Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Host Factors Associated with the Sindbis Virus RNA-Dependent RNA Polymerase: Role for G3BP1 and G3BP2 in Virus Replication

15 Apr 2010

Abstract excerpt

Sindbis virus (SINV) is the prototype member of the Alphavirus genus, whose members cause severe human diseases for which there is no specific treatment. To ascertain host factors important in the replication of the SINV RNA genome, we generated a SINV expressing nsP4, the viral RNA-dependent RNA polymerase, with an in-frame 3xFlag epitope tag. Proteomic analysis of nsP4-containing complexes isolated from cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to interferon and immune responses
Share to RNA Research and Splicing
Share to Viral Infections and Outbreaks Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20392851
DOI: 10.1128/jvi.01983-09

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Host Factors Associated with the Sindbis Virus RNA-Dependent RNA Polymerase: Role for G3BP1 and G3BP2 in Virus ReplicationPMID 20392851Read ↗

Interactions of Alphavirus nsP3 Protein with Host ProteinsSemantic proximity Read ↗

Increasing the Capping Efficiency of the Sindbis Virus nsP1 Protein Negatively Affects Viral InfectionSemantic proximity Read ↗

Roles of nonstructural protein nsP2 and Alpha/Beta interferons in determining the outcome of Sindbis virus infection.Semantic proximity Read ↗

Increasing the Capping Efficiency of the Sindbis Virus nsP1 Protein Negatively Affects Viral InfectionSemantic proximity Read ↗

Identification and Characterization of Sindbis Virus RNA-Host Protein InteractionsSemantic proximity Read ↗

TMEΜ45B Interacts with Sindbis Virus Nsp1 and Nsp4 and Inhibits Viral ReplicationSemantic proximity Read ↗

Changes of the secondary structure of the 5' end of the Sindbis virus genome inhibit virus growth in mosquito cells and lead to accumulation of adaptive mutations.Semantic proximity Read ↗

Hypervariable Domains of nsP3 Proteins of New World and Old World Alphaviruses Mediate Formation of Distinct, Virus-Specific Protein ComplexesSemantic proximity Read ↗

Sindbis Virus Infection Causes Cell Death by nsP2-Induced Transcriptional Shutoff or by nsP3-Dependent Translational ShutoffSemantic proximity Read ↗

Genome-wide analysis of protein–protein interactions and involvement of viral proteins in SARS-CoV-2 replicationSemantic proximity Read ↗

Hypervariable Domain of Eastern Equine Encephalitis Virus nsP3 Redundantly Utilizes Multiple Cellular Proteins for Replication Complex AssemblySemantic proximity Read ↗

The SARS-Coronavirus PLnc domain of nsp3 as a replication/transcription scaffolding proteinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.