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Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation.

1 Apr 1992

Abstract excerpt

Sindbis virus (SIN) is a small positive-strand enveloped RNA virus that infects a broad range of vertebrate and insect cells. A SIN vector (called dsSIN), designed for transient expression of heterologous RNAs and proteins, was engineered by inserting a second subgenomic mRNA promoter sequence into a nonessential region of the SIN genome. By using this vector, dsSIN recombinants have been constructed that express...

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PMID: 1372987
DOI: 10.1073/pnas.89.7.2679

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