Article
Circulating soluble factor-inhibiting natural killer (NK) activity of fresh peripheral blood mononuclear cells (PBMC) from inflammatory bowel disease (IBD) patients.
Clinical and experimental immunology - 1 Jan 1999
Giacomelli R, Passacantando A, Frieri G, Parzanese I, D'Alò S, Vernia P, Pimpo M T, Petrucci C, Caprilli R, Cifone M G, Tonietti G
Abstract excerpt
This study was performed in order to assess the cytotoxic activity, both natural (NK) and antibody-dependent (ADCC), of PBMC from 38 IBD patients and correlate it with their clinical features. Cytotoxicity assays were performed using sensitive target cells for NK and ADCC activities. In some experiments, highly purified NK cells, obtained both by Percoll density gradient and by co-culturing non-adherent PBMC with...
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