Article
Replication and persistence of simian immunodeficiency virus variants after passage in macaque lymphocytes and established human cell lines.
Journal of virology - 1 Mar 1993
Rudensey L M, Papenhausen M D, Overbaugh J
Abstract excerpt
In lentivirus infections, there are typically few cells in the host that harbor the provirus. For this reason, molecular clones of human and simian immunodeficiency viruses (HIV and SIV) are generally derived after passage and amplification of the virus in cell culture. To determine whether SIV v...
Topics
- Amino Acid Sequence
- Animals
- Cell Line
- Cloning, Molecular
- Gene Deletion
- Gene Products, env
- Genetic Variation
- Humans
- Lymphocytes
- Macaca
- Molecular Sequence Data
- Polymerase Chain Reaction