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Article

Complete Freund's adjuvant-induced T cells prevent the development and adoptive transfer of diabetes in nonobese diabetic mice.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 1993

Qin H Y, Sadelain M W, Hitchon C, Lauzon J, Singh B

Abstract excerpt

Insulin-dependent diabetes mellitus is an autoimmune disease that is characterized by the destruction of insulin-producing beta cells in the islet of Langerhans. We have recently reported that the induction of the disease in nonobese diabetic (NOD) mice can be prevented by a single injection of CFA. In this study, we have explored the cellular basis and the time course of the disease protection. Since CFA...

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PMID: 8436836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Complete Freund's adjuvant-induced T cells prevent the development and adoptive transfer of diabetes in nonobese diabetic mice.PMID 8436836Read ↗

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Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice.Semantic proximity Read ↗

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Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution.Semantic proximity Read ↗

Islet-specific T cell clones transfer diabetes to nonobese diabetic (NOD) F1 mice.Semantic proximity Read ↗

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