Article
[Frequency of occurrence of apolipoprotein E isoforms in patients with various types of hyperlipoproteinemias].
Casopis lekaru ceskych - 23 Aug 1999
Vrablík M, Horínek A, Ceska R, Poledne R, Hubácek M
Abstract excerpt
BACKGROUND: Apolipoprotein E is a polymorphic protein playing a crucial role in the metabolism of plasma lipoproteins. Three alleles referred to as epsilon 2, epsilon 3 and epsilon 4 code for three common isoforms of apoE. The most frequent allele in the population at large is epsilon 3 allele. epsilon 2 and epsilon 4 alleles are connected with lipoprotein disorders as well as with other diseases. The aim of our...
Topics
- Alleles
- Apolipoproteins E
- Female
- Humans
- Hyperlipoproteinemias
- Male