A novel PCR-based methodology to determine TAP allele frequencies in population studies.

doi:10.1111/j.1399-0039.1998.tb03030.x

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Article

A novel PCR-based methodology to determine TAP allele frequencies in population studies.

Tissue antigens - 1 Jul 1998

Perry C L, Mijovic C H, Cockram C S, Yeung V T, Jenkins D, Barnett A H

Abstract excerpt

The TAP genes have been extensively studied as candidate susceptibility genes for autoimmune and infectious diseases. TAP1 and TAP2 have two and three polymorphic sites respectively which are used for the allele assignment following WHO nomenclature. The usual techniques employed to determine the...

Topics

Alleles
Antiporters
Carrier Proteins
Gene Frequency
Humans
Immunoglobulins
Membrane Transport Proteins
Polymerase Chain Reaction

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