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Article

Polymorphisms in the TAP2 gene and their association with rheumatoid arthritis.

Clinical and experimental rheumatology - 1 Jan 2000

Singal D P, Ye M, Qiu X, D'Souza M

Abstract excerpt

The human major histocompatibility complex (MHC) contains two closely related genes (TAP) that encode a family of transporter proteins. It is known that the TAP genes, like other MHC (class I and class II) genes, are polymorphic. In this study we investigated the polymorphisms in the ATP-binding domain of the TAP2 gene and examined the relationship of these polymorphisms to susceptibility to rheumatoid arthritis...

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Source

Identifiers

PMID: 8162639

Genes

TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Polymorphisms in the TAP2 gene and their association with rheumatoid arthritis.PMID 8162639Read ↗

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Association of TAP2 polymorphism with rheumatoid arthritis is secondary to allelic association with HLA-DRB1.Semantic proximity Read ↗

TAP2 alleles in inflammatory arthritis.Semantic proximity Read ↗

Polymorphism of human major histocompatibility complex-encoded transporter associated with antigen processing (TAP) genes and susceptibility to juvenile rheumatoid arthritis.Semantic proximity Read ↗

Analysis of the MHC-encoded transporters TAP1 and TAP2 in rheumatoid arthritis: linkage with DR4 accounts for the association with a minor TAP2 allele.Semantic proximity Read ↗

TAP2D is associated with HLA-B44 and DR4 and may contribute to rheumatoid arthritis and Felty's syndrome susceptibility.Semantic proximity Read ↗

Alleles and haplotypes of the MHC-encoded ABC transporters TAP1 and TAP2.Semantic proximity Read ↗

The MHC2TA -168A/G polymorphism and risk for rheumatoid arthritis: a meta-analysis of 6861 patients and 9270 controls reveals no evidence for association.Semantic proximity Read ↗

Correlations and Influence of TAP2 Genes Polymorphisms and Systemic Lupus Erythematosus Propensity.Semantic proximity Read ↗

Role of the MHC2TA gene in autoimmune diseases.Semantic proximity Read ↗

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