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Article

Prognostic relevance of acquired uniparental disomy in serous ovarian cancer.

Molecular cancer - 3 Feb 2015

Tuna Musaffe, Ju Zhenlin, Smid Marcel, Amos Christopher I, Mills Gordon B

Abstract excerpt

BACKGROUND: Acquired uniparental disomy (aUPD) can lead to homozygosity for tumor suppressor genes or oncogenes. Our purpose is to determine the frequency and profile aUPD regions in serous ovarian cancer (SOC) and investigated the association of aUPD with clinical features and patient outcomes. METHODS: We analyzed single nucleotide polymorphism (SNP) array-based genotyping data on 532 SOC specimens from The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25644622
DOI: 10.1186/s12943-015-0289-1
PMCID: PMC4320828

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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