PCR analysis of DNA from 70-year-old sections of rodless retina demonstrates identity with the mouse rd defect.

Abstract excerpt

Rodless retina (gene symbol, r) was discovered in mice by Keeler 70 years ago and was first described in this journal as an autosomal recessive mutation leading to "the absence of the visual cells (rods), the external nuclear layer, and the external molecular layer" [Keeler, C. E. (1924) Proc. Natl. Acad. Sci. USA 10, 329-333]. The mutation was studied by Keeler and others in the United States and Europe over the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Photoreceptor and optogenetics research
• Share to Retinal Development and Disorders
• Share to Retinal Diseases and Treatments