Article
[Mechanisms of molecular development of human glioma].
Der Nervenarzt - 1 Aug 1993
Schlegel U
Abstract excerpt
Malignant gliomas present a difficult therapeutic problem. Within the last ten years, however, some of the molecular mechanisms have been disclosed that are involved in brain tumour development. According to these results the occurrence of a malignant tumour cell is the result of a multistage process, which involves mutations in several genes. These mutations affect genes regulating cellular proliferation and...
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