Article
[Genes implicated in glial tumors].
Morphologie : bulletin de l'Association des anatomistes - 1 Jun 2000
Sanson M, Marie Y, Huguet S, He J, Hoang-Xuan K
Abstract excerpt
Because of the absence of specific marker, the histological classification of gliomas remain controversial. Identifying the genetic alterations involved in gliomas makes it possible to define specific molecular pathway of tumoral progression and to define markers of prognostic and diagnostic relevance. For example, p53 mutations are frequent in low grade astrocytoma, anaplastic astrocytoma and secondary...
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