Article
Potential problems in estimating the male-to-female mutation rate ratio from DNA sequence data.
Journal of molecular evolution - 1 Aug 1993
Shimmin L C, Chang B H, Hewett-Emmett D, Li W H
Abstract excerpt
It is commonly believed that the rate of mutation is much higher in males than in females because the number of germ-cell divisions per generation is much larger in males than in females. However, the precise magnitude of the male-to-female mutation rate ratio (alpha m) remains unknown. Recently there have been efforts to estimate alpha m by using DNA sequence data from different species. We have studied the...
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